Search results for "running capacity"
showing 2 items of 2 documents
Effects of intrinsic aerobic capacity, aging and physical activity on interleukin-15 protein level in serum and skeletal muscle
2015
Myokines are cytokines and other peptides produced in muscle that can transmit autocrine, paracrine or endocrine signals to other tissues. This is a potential way for exercise to carry out its beneficial effects on different parts of the body. Interleukin-15 (IL-15) is a myokine that has been shown to exert beneficial effects on multiple tissues: skeletal muscle, adipose tissue, bone and skin. Muscle-derived IL-15 signaling remains to be fully elucidated. It is known that the expression and signaling is affected by aging, exercise, and intrinsic aerobic capacity. The purpose of this study was to assess the effects of intrinsic aerobic capacity, aging and physical activity separately and in …
Genotype determining aerobic exercise capacity associates with behavioral plasticity in middle-aged rats
2023
Good aerobic fitness associates positively with cognitive performance and brain health and conversely, low aerobic fitness predisposes to neurodegenerative diseases. To study how genotype together with exercise, started at older age, affects brain and behavior, we utilized rats that differ in inherited aerobic fitness. Rats bred for Low Capacity for Running (LCR) are shown to display less synaptic plasticity and more inflammation in the hippocampus and perform worse than rats bred for a High Capacity for Running (HCR) in tasks requiring flexible cognition. Here we used middle-aged (∼ 16 months) HCR and LCR rats to study how genotype and sex associate with anxiety and neural information filt…